The Childhood Cancer Survivor Study

The research findings, drawn from the reports of nearly 10,400 people whose cancers were diagnosed between 1970 and 1986, alter the context of a stunning medical success over the past 35 years - a period when children's survival rates from cancer went from virtually zero to nearly 80 per cent.

Despite drugs that are less toxic and technology that can precisely target malignant masses, youngsters and teenagers in treatment are likely to confront the same concerns, experts say.

The Childhood Cancer Survivor Study has prompted many survivors and their families to reconsider what the future holds - some with equanimity, others with sadness, fear or denial.